BDBM50496215 CHEMBL3125620

SMILES CC(C)(C)NC(=O)Nc1nc(Cl)c(-c2ccc(cc2)-c2cccnc2)n(CC(=O)Nc2ccccc2C(=O)NS(=O)(=O)c2ccc(cc2)C(F)(F)F)c1=O

InChI Key InChIKey=ZALFYELKEPOBLO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50496215   

TargetGenome polyprotein(Hepatitis C Virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50496215(CHEMBL3125620)
Affinity DataKi:  740nMAssay Description:Inhibition of full-length HCV NS3 protease A156T mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50496215(CHEMBL3125620)
Affinity DataKi:  1.52E+3nMAssay Description:Inhibition of full-length HCV NS3 protease D168V mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50496215(CHEMBL3125620)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of full-length HCV NS3 protease R155K mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed