BDBM50496565 CHEMBL3133868

SMILES OC(=O)C(O)=O.COc1ccccc1N1CCN(C\C=C\CNC(=O)c2cc3cc(OCCOCCF)ccc3[nH]2)CC1

InChI Key InChIKey=ZJCJUHTYZBBRTE-SNAWJCMRSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50496565   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50496565(CHEMBL3133868)
Affinity DataKi:  3.80nMAssay Description:Displacement of [125I]ABN from human D3 receptor transfected in HEK-293 cell membrane after 60 mins by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50496565(CHEMBL3133868)
Affinity DataKi:  120nMAssay Description:Displacement of [125I]ABN from human D2 receptor transfected in HEK-293 cell membrane after 60 mins by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50496565(CHEMBL3133868)
Affinity DataKi:  360nMAssay Description:Displacement of [125I]ABN from human D4 receptor transfected in HEK-293 cell membrane after 60 mins by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50496565(CHEMBL3133868)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]pentazocine from sigma1 receptor in guinea pig brain membrane after 90 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed