BDBM50497007 CHEMBL3235898
SMILES OC(=O)c1ccc(cc1Cl)-c1ccc(\C=C2\C(=O)NN(C2=O)c2cccc(Cl)c2)o1
InChI Key InChIKey=XVLQZWSQEMKEIL-YBEGLDIGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50497007
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKi: 2.80E+5nMAssay Description:Inhibition of Cys5-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measu...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKd: 1.52E+4nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) interaction assessed as compound's equilibrium dissociation constant after 60 mins by fluorescence anisotro...More data for this Ligand-Target Pair
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataKd: >1.50E+5nMAssay Description:Binding affinity to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance ...More data for this Ligand-Target Pair