BDBM50498655 CHEMBL1895209
SMILES COc1cc2nc(nc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC)N1CCN(C)CC1
InChI Key InChIKey=LDFAJFPHFKEJOI-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50498655
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 101nMAssay Description:Inhibition of G9a (unknown origin) using [histone H3 1 to 25 residues] and SAM substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-36 specific(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.12E+5nMAssay Description:Inhibition of human NSD1-SET using histone H3.1 as substrate incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Imperial College London
Curated by ChEMBL
Imperial College London
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of EHMT2 (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase NSD3(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 9.50E+4nMAssay Description:Inhibition of human NSD3-SET using histone H3.1 as substrate incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase NSD2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human NSD2-SET using histone H3.1 as substrate incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair