BDBM50498797 CHEMBL3105545

SMILES COc1ccc(cc1OC)[C@@H](O)[C@@H](C)Oc1ccc(cc1OC)[C@H]1O[C@@H]([C@H](C)[C@H]1C)c1ccc(OC)c(OC)c1

InChI Key InChIKey=JYXVAMLAJSGCDL-PLCQSOOISA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50498797   

TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Shandong University

Curated by ChEMBL

LigandBDBM50498797(CHEMBL3105545)Copy SMILESCopy InChI

Affinity DataIC50:  20nMAssay Description:Activation of HIF1 in human T47D cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Duke University

Curated by ChEMBL

LigandBDBM50498797(CHEMBL3105545)Copy SMILESCopy InChI

Affinity DataIC50:  320nMAssay Description:Inhibition of HIF1 in human HEK293T cells transfected with pGL3-5HRE-VEGF and pRL-SV40 after 24 hrs by dual luciferase reporter assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI