BDBM50499246 CHEMBL3735376

SMILES Fc1ccc(cc1)-n1ncc2C[C@@]3(CN(CCC3=Cc12)S(=O)(=O)c1ccc(F)cc1)C(=O)c1ccccn1

InChI Key InChIKey=AJJYMQGHGPINNM-NDEPHWFRSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50499246   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Corcept Therapeutics

Curated by ChEMBL
LigandPNGBDBM50499246(CHEMBL3735376)
Affinity DataKi:  0.130nMAssay Description:Binding affinity to human recombinant glucocorticoid receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Corcept Therapeutics

Curated by ChEMBL
LigandPNGBDBM50499246(CHEMBL3735376)
Affinity DataKi:  16nMAssay Description:Antagonist activity at glucocorticoid receptor in human HepG2 cells assessed as inhibition of glucocorticoid-induced TAT activity after 24 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Corcept Therapeutics

Curated by ChEMBL
LigandPNGBDBM50499246(CHEMBL3735376)
Affinity DataIC50:  980nMAssay Description:Inhibition of human ERG by patch clamp techniqueMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed