BDBM50499592 CHEMBL3741490

SMILES COCCOc1cc2c(Nc3cccc(c3)C#C)ncnc2cc1OCCO

InChI Key InChIKey=MTLKTHNRZJKPRP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50499592   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50499592(CHEMBL3741490)
Affinity DataIC50:  1nMAssay Description:Inhibition of EGFR (unknown origin) using tyrosine 4 as substrate by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50499592(CHEMBL3741490)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human COX-2 preincubated for 15 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Guangzhou Institutes Of Biomedicine And Health

Curated by ChEMBL
LigandPNGBDBM50499592(CHEMBL3741490)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Ovine COX-1 preincubated for 15 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed