BDBM50500154 CHEMBL3746870
SMILES CCOC(=O)CCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1
InChI Key InChIKey=VXOSHKVRVDJROE-HHHXNRCGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50500154
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]propionyl-pNPY from NPY1R in HEL cells after 60 to 90 mins by flow cytometric analysisMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.490nMAssay Description:Displacement of [3H]UR-MK136 from NPY1R in human SK-N-MC cells by radioligand binding assayMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of Cy5-pNPY from human NPY2R expressed in CHO cells by flow cytometric analysisMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of Cy5-pNPY from human NPY5R expressed in HEC cells by flow cytometric analysisMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of Cy5-[K4]hPP from human NPY4R expressed in CHO cells by flow cytometric analysisMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 10 secs by Fura-2 dye bas...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 20 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataIC50: 0.151nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 10 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataIC50: 0.162nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 5 mins by Fura-2 dye base...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataIC50: 0.513nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 1 min by Fura-2 dye based...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataIC50: 0.105nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 15 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataIC50: 0.331nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 2 mins by Fura-2 dye base...More data for this Ligand-Target Pair