BDBM50500358 CHEMBL3746482

SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1-c1cn[nH]c1

InChI Key InChIKey=BUHLWVQDHMLTPT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500358   

TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50500358(CHEMBL3746482)
Affinity DataIC50:  64nMAssay Description:Inhibition of wild type EML4-ALK (unknown origin) expressed in mouse Ba/F3 cells assessed as cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed