BDBM50500718 CHEMBL3751997

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@@H](CCCCCF)P(O)(O)=O

InChI Key InChIKey=CZWJAEJHLBICAX-LJQANCHMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50500718   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50500718(CHEMBL3751997)
Affinity DataIC50:  19nMAssay Description:Inhibition of human MMP9 using (7-methoxycoumarin-4-yl) acetyl pro-Leu-Gly-Leu-[3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl]-Ala-Arg-NH2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50500718(CHEMBL3751997)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of human MMP2 using (7-methoxycoumarin-4-yl) acetyl pro-Leu-Gly-Leu-[3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl]-Ala-Arg-NH2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Westf£Lische Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50500718(CHEMBL3751997)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of MMP13 (unknown origin) using (7-methoxycoumarin-4-yl) acetyl pro-Leu-Gly-Leu-[3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl]-Ala-Arg-NH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed