BDBM50502588 CHEMBL4439533

SMILES Cc1nnc(Nc2ccc(nc2)-c2ccc(cc2)[C@H]2CC[C@H](CC(O)=O)CC2)o1

InChI Key InChIKey=XBESUWXKHAMBQU-WKILWMFISA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50502588   

TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502588(CHEMBL4439533)
Affinity DataEC50:  206nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502588(CHEMBL4439533)
Affinity DataIC50:  540nMAssay Description:Inhibition of recombinant human his-tagged DGAT1 expressed in Sf9 insect cells using oleoyl-CoA and diolein as substrates incubated for 30 mins by LC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed