BDBM50502592 CHEMBL4555623

SMILES CCc1nc(C)c(o1)C(=O)Nc1ccc(nc1)-c1ccc(cc1)C12CCC(CC(O)=O)(CC1)OC2

InChI Key InChIKey=UFIKUWNNXLDUCS-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50502592   

TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502592(CHEMBL4555623)
Affinity DataEC50:  98nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50502592(CHEMBL4555623)
Affinity DataIC50:  390nMAssay Description:Inhibition of recombinant human his-tagged DGAT1 expressed in Sf9 insect cells using oleoyl-CoA and diolein as substrates incubated for 30 mins by LC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed