BDBM50503883 CHEMBL4443691

SMILES CCCCc1nc(C)c(CNC(=O)[C@@H](S)CC(C)C)n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key InChIKey=GFAPVUXBADBZKC-SANMLTNESA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503883   

TargetType-1 angiotensin II receptor(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50503883(CHEMBL4443691)
Affinity DataKi:  200nMAssay Description:Displacement of Europium-labeled angiotensin-2 from human AT1 receptor expressed in CHOK1 cell membranes after 120 mins by DELFIAMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50503883(CHEMBL4443691)
Affinity DataIC50:  0.631nMAssay Description:Inhibition of NEP (unknown origin) preincubated for 10 mins followed by fluorogenic substrate addition and measured after 20 mins by fluorescence ass...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed