BDBM50505060 CHEMBL4449080

SMILES Cn1ncc(NC(=O)c2csc(n2)-c2c(F)cccc2F)c1N1CCC[C@H](N)CC1

InChI Key InChIKey=YJMUKULIAJBLOM-LBPRGKRZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50505060   

TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50505060(CHEMBL4449080)
Affinity DataKi:  0.400nMAssay Description:Inhibition of recombinant human PIM3 using FAM-pimtide as substrate after 90 mins by Z-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50505060(CHEMBL4449080)
Affinity DataKi:  0.600nMAssay Description:Inhibition of recombinant human PIM1 using FAM-pimtide as substrate after 90 mins by Z-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50505060(CHEMBL4449080)
Affinity DataKi:  8.10nMAssay Description:Inhibition of recombinant human PIM2 using FAM-pimtide as substrate after 90 mins by Z-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed