BDBM50505779 CHEMBL4461771
SMILES OC(=O)CC1CC(=O)N1
InChI Key InChIKey=PFYZSIGLKDYGAG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50505779
Affinity DataEC50: 1.03E+3nMAssay Description:Agonist activity at alpha5beta1 integrin receptor in human K562 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated for 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of fibronectin binding to alpha4bbeta1 isolated from human Jurkat E6.1 cells incubated for 1 hr by scintillation-proximity assay based com...More data for this Ligand-Target Pair
Affinity DataIC50: 265nMAssay Description:Inhibition of fibrinogen binding to alpha2bbeta3 isolated from human HEL cells incubated for 1 hr by scintillation-proximity assay based competitive ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of fibronectin binding to alpha5beta1 isolated from human K562 cells incubated for 1 hr by scintillation-proximity assay based competitive...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Antagonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fi...More data for this Ligand-Target Pair
Affinity DataEC50: 376nMAssay Description:Agonist activity at alphaVbeta5 in human MCF7 cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaVbeta6 in human HT-29 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronecti...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Antagonist activity at alphaVbeta6 in human HT-29 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibron...More data for this Ligand-Target Pair
Affinity DataEC50: 1.03E+3nMAssay Description:Agonist activity at alpha5beta1 in human K562 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
Affinity DataEC50: 311nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Antagonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.63E+3nMAssay Description:Antagonist activity at alphaLbeta2 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to ICAM1 pre-incubated for 30 mins before ICAM1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of fibronectin binding to human recombinant alphaVbeta3 expressed in HEK293 cells incubated for 1 hr by scintillation-proximity assay base...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of fibrinogen binding to alphaVbeta5 isolated form human mCf7 cells incubated for 1 hr by scintillation-proximity assay based competitive ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of fibronectin binding to alphaVbeta6 isolated form human HT-29 cells incubated for 1 hr by scintillation-proximity assay based competitiv...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Antagonist activity at alphaVbeta3 integrin receptor in human SK-MEL-24 cells assessed as reduction in fibronectin-induced cell adhesion pre-incubate...More data for this Ligand-Target Pair