BDBM50505946 CHEMBL4565615::US11168095, Example 138
SMILES C[C@H]1CCCn2cnnc2-c2cccc(NC(=O)c3ccccc3O1)n2
InChI Key InChIKey=RLJLYJODLXFSPU-ZDUSSCGKSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50505946
Affinity DataIC50: 165nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Table 2: Alternatively, the protein kinase activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Cor...More data for this Ligand-Target Pair
Affinity DataIC50: 969nMAssay Description:Inhibition of V5 tagged human ASK1 expressed in HEK-293T cells assessed as reduction in T838 autophosphorylation incubated for 1 hrMore data for this Ligand-Target Pair