BDBM50505956 CHEMBL4473364::US11168095, Example 28
SMILES CS(=O)(=O)c1ccc2OCCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3
InChI Key InChIKey=OFDCLFNYWAGEEP-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50505956
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of V5 tagged human ASK1 expressed in HEK-293T cells assessed as reduction in T838 autophosphorylation incubated for 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Table 1: Briefly, 20 μL aliquots of a 1.5× stock of ASK1, STK Substrate 3 and Assay Buffer were distributed in the wells of a white 384 well Opt...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair