BDBM50505957 CHEMBL4591648
SMILES C[C@@H]1CCOc2cc(F)c(cc2C(=O)Nc2cccc(n2)-c2nncn2C1)-c1cnn(CCN(C)C)c1
InChI Key InChIKey=KJXWPROLOCNBKX-QGZVFWFLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50505957
Affinity DataIC50: 8nMAssay Description:Inhibition of human ASK1 using myelin basic protein substrate pre-incubated for 20 mins before [33P]-ATP addition and measured after 2 hrs by filter-...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of V5 tagged human ASK1 expressed in HEK-293T cells assessed as reduction in T838 autophosphorylation incubated for 1 hrMore data for this Ligand-Target Pair