BDBM50506122 CHEMBL4531005
SMILES CC(C)c1[nH]c2nc(N)nn2c(=O)c1Cc1cccc(Cl)c1Cl
InChI Key InChIKey=KLBHHUODQVCBKX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50506122
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]-CCR2-RA-[R] from human CCR2 expressed in human U2OS cells incubated for 2 hrs by scintillation spectrometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]-CCR2-RA-[R] from human CCR2 expressed in human U2OS cells incubated for 2 hrs by scintillation spectrometric methodMore data for this Ligand-Target Pair
Affinity DataEC50: 4.5nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as pEC50 for CCL3-stimulated [35S]GT...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR2 expressed in human U2OS cell membranes assessed as EC50 for CCL2-stimulated [35S]GTP...More data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR2 expressed in human U2OS cell membranes assessed as EC50 for CCL2-stimulated [35S]GTP...More data for this Ligand-Target Pair
Affinity DataEC50: 56nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR2 expressed in human U2OS cell membranes assessed as EC50 for CCL2-stimulated [35S]GTP...More data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as EC50 for CCL3-stimulated [35S]GTP...More data for this Ligand-Target Pair
Affinity DataIC50: 81.3nMAssay Description:Antagonist activity at human TEV cleavage site-linked CCR5 expressed in human U2OS cells harboring beta-lactamase reporter gene assessed as inhibitio...More data for this Ligand-Target Pair
Affinity DataEC50: 7.20nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as pEC50 for CCL3-stimulated [35S]GT...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR2 expressed in human U2OS cell membranes assessed as pEC50 for CCL2-stimulated [35S]GT...More data for this Ligand-Target Pair
Affinity DataEC50: 54nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR2 expressed in human U2OS cell membranes assessed as pEC50 for CCL2-stimulated [35S]GT...More data for this Ligand-Target Pair
Affinity DataEC50: 7.20nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as pEC50 for CCL3-stimulated [35S]GT...More data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as EC50 for CCL3-stimulated [35S]GTP...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human TEV cleavage site-linked CCR2b expressed in human U2OS cells harboring beta-lactamase reporter gene assessed as inhibiti...More data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Antagonist activity at human TEV cleavage site-linked CCR5 expressed in human U2OS cells harboring beta-lactamase reporter gene assessed as inhibitio...More data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR2 expressed in human U2OS cell membranes assessed as pEC50 for CCL2-stimulated [35S]GT...More data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as EC50 for CCL3-stimulated [35S]GTP...More data for this Ligand-Target Pair