BDBM50506123 CHEMBL4516788

SMILES CC(C)c1[nH]c2nc(N)nn2c(=O)c1Cc1cc(Cl)cc(Cl)c1

InChI Key InChIKey=SCSTUPQPTWXCHZ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50506123   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506123(CHEMBL4516788)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]-CCR2-RA-[R] from human CCR2 expressed in human U2OS cells incubated for 2 hrs by scintillation spectrometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506123(CHEMBL4516788)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]-CCR2-RA-[R] from human CCR2 expressed in human U2OS cells incubated for 2 hrs by scintillation spectrometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506123(CHEMBL4516788)
Affinity DataIC50:  324nMAssay Description:Antagonist activity at human TEV cleavage site-linked CCR5 expressed in human U2OS cells harboring beta-lactamase reporter gene assessed as inhibitio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506123(CHEMBL4516788)
Affinity DataIC50:  323nMAssay Description:Antagonist activity at human TEV cleavage site-linked CCR5 expressed in human U2OS cells harboring beta-lactamase reporter gene assessed as inhibitio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed