BDBM50506476 CHEMBL4547484::US11311527, Cpd ID I-2::US11376246, Cpd ID I-2::US11576906, Compound I-2

SMILES CCn1cccc(NCc2cc3cc(Cl)ccc3[nH]c2=O)c1=O

InChI Key InChIKey=GWBZTYSDSZBEJE-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506476   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM50506476(CHEMBL4547484 | US11311527, Cpd ID I-2 | US1137624...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound 1 was not initially reported as having the greatest biochemical potency compared to reports for certain other small molecule inhibitors of m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Forma Therapeutics

US Patent
LigandPNGBDBM50506476(CHEMBL4547484 | US11311527, Cpd ID I-2 | US1137624...)
Affinity DataIC50:  550nMAssay Description:Compound 1 was not initially reported as having the greatest biochemical potency compared to reports for certain other small molecule inhibitors of m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent