BDBM50506666 CHEMBL4455326

SMILES COc1cc(\C=C2/SC(=O)N(CC(O)=O)C2=O)ccc1OCc1ccccc1

InChI Key InChIKey=JWKUAZOIQZNCES-YVLHZVERSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506666   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506666(CHEMBL4455326)
Affinity DataIC50:  323nMAssay Description:Inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in NADPH oxidation using L-idos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50506666(CHEMBL4455326)
Affinity DataIC50:  1.51E+5nMAssay Description:Inhibition of human full-length GST-fused PTP1B expressed in bacterial expression system using pNPP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed