BDBM50507551 CHEMBL4587222

SMILES CCN1CCN(CCCOc2cc3nccc(Oc4c(F)cc(NC(=O)NN5C(SCC5=O)c5c(F)cccc5F)cc4F)c3cc2OC)CC1

InChI Key InChIKey=GZVQZLVAKXRTHU-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50507551   

TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Zhuhai Campus Of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50:  53nMAssay Description:Inhibition of AXL (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Zhuhai Campus Of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50:  15nMAssay Description:Inhibition of c-Met (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Zhuhai Campus Of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50:  64nMAssay Description:Inhibition of c-Kit (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Zhuhai Campus Of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50:  850nMAssay Description:Inhibition of KDR (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Zhuhai Campus Of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ALK (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhuhai Campus Of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50:  520nMAssay Description:Inhibition of EGFR (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Zhuhai Campus Of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of IGF-1R (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Zhuhai Campus Of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HER-2 (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Zhuhai Campus Of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of Ron (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Zhuhai Campus Of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50507551(CHEMBL4587222)
Affinity DataIC50:  240nMAssay Description:Inhibition of c-Src (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed