BDBM50507805 CHEMBL4545195

SMILES CCCN(CCC)C(=O)c1cc(Cl)cc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNC(C)(C)c1cccc(OC)c1

InChI Key InChIKey=MZZICJGCOVKCKO-IOWSJCHKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50507805   

TargetCathepsin D(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50507805(CHEMBL4545195)
Affinity DataIC50:  96nMAssay Description:Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasmepsin IV [1-448](Plasmodium falciparum)
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50507805(CHEMBL4545195)
Affinity DataIC50:  8nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 4 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed