BDBM50508564 CHEMBL4553861
SMILES Cn1ccc2ccc(cc12)-c1cc(Nc2ccccc2S(=O)(=O)NCc2cncnc2)cc2nccnc12
InChI Key InChIKey=FHKKLQIBTXYWGR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50508564
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
Selvita
Curated by ChEMBL
Selvita
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PFKFB3 in human HCT116 cell lysates assessed as reduction in glycolytic-flux induced fructose-2,6-bisphosphate formation using fructose...More data for this Ligand-Target Pair
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
Selvita
Curated by ChEMBL
Selvita
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G...More data for this Ligand-Target Pair