BDBM505087 US11040966, Example 6.1::[5-(4-Fluoro-phenyl)-2-methyl-thiazol-4-yl]-[(S)-2-(5-methoxy-1H-benzoimidazol-2-yl)-4-methylene-pyrrolidin-1-yl]-methanone

SMILES COc1ccc2[nH]c(nc2c1)[C@@H]1CC(=C)CN1C(=O)c1nc(C)sc1-c1ccc(F)cc1

InChI Key InChIKey=YEGQZEMOXGQICN-FQEVSTJZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 505087   

TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM505087(US11040966, Example 6.1 | [5-(4-Fluoro-phenyl)-2-m...)
Affinity DataIC50:  33nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM505087(US11040966, Example 6.1 | [5-(4-Fluoro-phenyl)-2-m...)
Affinity DataIC50:  367nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent