BDBM50509149 CHEMBL3421836

SMILES C[C@@H]1N([C@@H](CO)Cc2c(CC(C)(C)O)cccc12)C(=O)Cc1c(Cl)cccc1Cl

InChI Key InChIKey=QBKZBAUOKUPKIJ-GOEBONIOSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50509149   

TargetD(1A) dopamine receptor(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50509149(CHEMBL3421836)
Affinity DataEC50:  76nMAssay Description:Positive allosteric modulator activity at human D1 receptor stably expressed in HEK293 cells assessed as potentiation of EC20 dopamine-induced cAMP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50509149(CHEMBL3421836)
Affinity DataEC50:  3.70nMAssay Description:Positive allosteric modulation of human D1R expressed in HEK293 cells assessed as increase in dopamine-induced cAMP accumulation after 60 mins by HTR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed