BDBM50509151 CHEMBL3421730

SMILES C[C@@H]1N([C@@H](CO)Cc2c1cccc2C(C)(C)O)C(=O)Cc1c(Cl)cccc1Cl

InChI Key InChIKey=CWRORBWPLQQFMX-UONOGXRCSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50509151   

TargetD(1A) dopamine receptor(Mus musculus (Mouse))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50509151(CHEMBL3421730)
Affinity DataEC50:  312nMAssay Description:Positive allosteric modulation of mouse D1R expressed in HEK293 cells assessed as increase in dopamine-induced cAMP accumulation after 60 mins by HTR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50509151(CHEMBL3421730)
Affinity DataEC50:  14nMAssay Description:Positive allosteric modulator activity at human D1 receptor stably expressed in HEK293 cells assessed as potentiation of EC20 dopamine-induced cAMP a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50509151(CHEMBL3421730)
Affinity DataEC50:  162nMAssay Description:Positive allosteric modulation of rat D1R expressed in HEK293 cells assessed as increase in dopamine-induced cAMP accumulation after 60 mins by HTRF ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50509151(CHEMBL3421730)
Affinity DataEC50:  5.80nMAssay Description:Positive allosteric modulation of human D1R expressed in HEK293 cells assessed as increase in dopamine-induced cAMP accumulation after 60 mins by HTR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed