BDBM50509350 CHEMBL4441993
SMILES Cl.CN(C)CCOc1ccc2c3CCN(Cc3c(=O)oc2c1C)C(=O)c1ccc(cc1)C(O)=O
InChI Key InChIKey=MIJQUVPEENIREO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50509350
TargetC-1-tetrahydrofolate synthase, cytoplasmic(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant MTHFD1 (unknown origin) using THF as substrate incubated for 30 mins in presence of NADMore data for this Ligand-Target Pair
TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant MTHFD2 (unknown origin) using THF as substrate incubated for 30 mins in presence of NADMore data for this Ligand-Target Pair