BDBM50509565 CHEMBL3558130
SMILES OC(=O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccnc23)c(F)c1
InChI Key InChIKey=MOBGLSPZTAMCCO-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50509565
Affinity DataIC50: 90nMAssay Description:Allosteric inhibition of yeast GAL4 DNA domain-fused RORgammat LBD (97 to 518 residues) (unknown origin) expressed in HEK293T cells after 20 to 22 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Allosteric inhibition of RORgammaT in IL-1B/IL-23/IL-2/IL-6/T-Activator CD3/28 Dynabeads-stimulated human PBMC cells assessed as reduction in Th17 di...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human GAL4-fused RORgammat LBD transfected in Escherichia coli BL21(DE3) cell measured after 16 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Allosteric inhibition of recombinant His6-tagged RORgammat LBD (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of bio...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]rosiglitazone from human recombinant PPARgamma LBD expressed in insect cells measured after 24 hrs by scintillation counting anal...More data for this Ligand-Target Pair