BDBM505098 US11066404, Example 1
SMILES CC1(C)Cc2cnc(Nc3ccc(cc3)S(N)(=O)=O)nc2N(C2CCCC2)C1=O
InChI Key InChIKey=WCNNCGJVXFEBGV-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 505098
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged full-length CDK2/Flag-tagged cyclinE1 expressed in baculovirus expression system using eIF4E-bi...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair