BDBM50509857 CHEMBL4474333

SMILES Oc1ccc(cc1)-c1c(nc2c(nccn12)N1CCOCC1)-c1ccc(Cl)cc1

InChI Key InChIKey=CZSKDVLQDHVZEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50509857   

TargetGlutamate receptor 1/Voltage-dependent calcium channel gamma-2 subunit(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50509857(CHEMBL4474333)
Affinity DataIC50:  10nMAssay Description:Negative allosteric modulation of recombinant human GluA1 flop isoform/TARPgamma2 expressed in HEK293 cells assessed as inhibition of glutamate-induc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel gamma-8 subunit(Rattus norvegicus)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50509857(CHEMBL4474333)
Affinity DataIC50: <1.00E+4nMAssay Description:Negative allosteric modulation of TARPgamma8 in rat hippocampal neurons assessed as inhibition of glutamate-induced current at 10 uM at -60 mV holdin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed