BDBM50510315 CHEMBL518323

SMILES Nc1ncc(cc1OCc1c(Cl)ccc(F)c1Cl)-c1cnn(c1)C1CCNCC1

InChI Key InChIKey=SZSQAKDNRSCZOY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510315   

TargetMitogen-activated protein kinase kinase kinase kinase 3(Homo sapiens (Human))
Biogen

Curated by ChEMBL
LigandPNGBDBM50510315(CHEMBL518323)
Affinity DataIC50:  39nMAssay Description:Inhibition of GLK (unknown origin) by alphascreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
East China University Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50510315(CHEMBL518323)
Affinity DataIC50:  572nMAssay Description:Inhibition of human recombinant N-terminal hexahistidine tagged JAK2 JH1 catalytic domain (835 to 1132 residues) expressed in baculovirus infected Sf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed