BDBM50510756 CHEMBL4447664
SMILES [H][C@]12C[C@@]3([H])C4=CCO[C@@]5([H])[C@H](N)C(=O)N6c7ccccc7[C@@]1(CCN2C4)[C@]6([H])[C@@]35[H]
InChI Key InChIKey=XHGQHKSZUGARHU-VJTNSULXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50510756
TargetGlycine receptor subunit alpha-1(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataKi: 741nMAssay Description:Displacement of [3H]strychnine from human glycine receptor subunit alpha-1 expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
TargetGlycine receptor subunit alpha-1(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response by fl...More data for this Ligand-Target Pair
TargetGlycine receptor subunit alpha-1/beta(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 7.76E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response b...More data for this Ligand-Target Pair
TargetGlycine receptor subunit alpha-1(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 194nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in HEK293 cells assessed as reduction in glycine-induced whole cell currents ...More data for this Ligand-Target Pair
TargetGlycine receptor subunit alpha-1/beta(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 7.70E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response b...More data for this Ligand-Target Pair
TargetGlycine receptor subunit alpha-1(Homo sapiens (Human))
The German University In Cairo
Curated by ChEMBL
The German University In Cairo
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response by fl...More data for this Ligand-Target Pair