BDBM50510757 CHEMBL4518537

SMILES [H][C@]12C[C@@]3([H])C4=CCO[C@@]5([H])[C@H](NC(=O)CC)C(=O)N6c7ccccc7[C@@]1(CCN2C4)[C@]6([H])[C@@]35[H]

InChI Key InChIKey=ZYQOFJMYFTVXSE-ODOYRXLASA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50510757   

TargetGlycine receptor subunit alpha-1(Homo sapiens (Human))
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50510757(CHEMBL4518537)
Affinity DataKi:  91nMAssay Description:Displacement of [3H]strychnine from human glycine receptor subunit alpha-1 expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1/beta(Homo sapiens (Human))
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50510757(CHEMBL4518537)
Affinity DataIC50:  147nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in HEK293 cells assessed as reduction in glycine-induced whole cell curre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1(Homo sapiens (Human))
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50510757(CHEMBL4518537)
Affinity DataIC50:  710nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1(Homo sapiens (Human))
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50510757(CHEMBL4518537)
Affinity DataIC50:  708nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1(Homo sapiens (Human))
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50510757(CHEMBL4518537)
Affinity DataIC50:  173nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in HEK293 cells assessed as reduction in glycine-induced whole cell currents ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1/beta(Homo sapiens (Human))
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50510757(CHEMBL4518537)
Affinity DataIC50:  2.19E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1/beta(Homo sapiens (Human))
The German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50510757(CHEMBL4518537)
Affinity DataIC50:  2.20E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed