BDBM50510954 CHEMBL4452449
SMILES CN1Cc2cc(cnc2C1=O)-c1ccc(s1)-c1cncc(NS(=O)(=O)c2cccc(c2)C(F)(F)F)c1
InChI Key InChIKey=IUYXCZYVISRDNV-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50510954
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of perforin in human KHYG-1 cells pre-treated with compound for 20 mins assessed as reduction in KHYG-1 cells-mediated cell lysis of human...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of perforin (unknown origin) assessed as reduction in perforin-mediated cell lysis in human Jurkat T cells incubated for 30 mins by 51Cr r...More data for this Ligand-Target Pair