BDBM50510961 CHEMBL4527624

SMILES Fc1ccc(c(F)c1)S(=O)(=O)Nc1cncc(c1)-c1ccc(s1)-c1ccc2C(=O)N(CCN3CCOCC3)Cc2c1

InChI Key InChIKey=SPMILTIXMLQTJX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50510961   

TargetPerforin-1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50510961(CHEMBL4527624)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of perforin (unknown origin) assessed as reduction in perforin-mediated cell lysis in human Jurkat T cells incubated for 30 mins by 51Cr r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed