BDBM50511123 CHEMBL4522193
SMILES CC(C)(C)c1ccc(cc1)N1CCN(CC1)S(=O)(=O)Nc1ccc(SCCc2ccccc2)cc1C(O)=O
InChI Key InChIKey=QNFWYMWAXZJAME-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50511123
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry
Curated by ChEMBL
National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKi: 73nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry
Curated by ChEMBL
National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKi: 84nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
National Institute Of Chemistry
Curated by ChEMBL
National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of N-terminal His6-tagged human Bcl-2 isoform 2 (1 to 34 residues and 92 to 202 residues with Bcl-xL sequence (35 to 50 residues) expresse...More data for this Ligand-Target Pair
Affinity DataKi: 3.50E+3nMAssay Description:Inhibition of N-terminal His6-tagged human Bcl-xL (with internal deletion of 45 to 85 amino acids and C-terminal truncation for 212 to 233 residues) ...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry
Curated by ChEMBL
National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKd: 490nMAssay Description:Binding affinity to immobilized biotin-labeled and N-terminal His6-tagged human Mcl-1 expressed in Escherichia coli Rosetta2 DE3 by biolayer interfer...More data for this Ligand-Target Pair
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry
Curated by ChEMBL
National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKd: 920nMAssay Description:Binding affinity to immobilized biotin-labeled and N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3...More data for this Ligand-Target Pair