BDBM50511128 CHEMBL4448621
SMILES OC(=O)c1cc(SCCc2ccccc2)ccc1NS(=O)(=O)c1ccccc1
InChI Key InChIKey=XJNPROORRVATHD-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50511128
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
National Institute Of Chemistry
Curated by ChEMBL
National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...More data for this Ligand-Target Pair
TargetBcl-2-related protein A1(Homo sapiens (Human))
National Institute Of Chemistry
Curated by ChEMBL
National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...More data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of N-terminal His6-tagged human Bcl-xL (with internal deletion of 45 to 85 amino acids and C-terminal truncation for 212 to 233 residues) ...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
National Institute Of Chemistry
Curated by ChEMBL
National Institute Of Chemistry
Curated by ChEMBL
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of N-terminal His6-tagged human Bcl-2 isoform 2 (1 to 34 residues and 92 to 202 residues with Bcl-xL sequence (35 to 50 residues) expresse...More data for this Ligand-Target Pair