BDBM50511432 CHEMBL4435945

SMILES COC(=O)Nc1cc2NCCCc2c(n1)-c1cccc(C)c1C

InChI Key InChIKey=AGJXLMPNEFXHGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50511432   

TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50511432(CHEMBL4435945)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of human recombinant human His-tagged MTH1 expressed in Escherichia coli BL21 (DE3) using 8-oxo-dGTP as substrate incubated for 15 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed