BDBM50512105 CHEMBL4587327

SMILES CC[C@H](NC(C)=O)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccc(cc2s1)C(=O)NC1CCNCC1

InChI Key InChIKey=MMCZPBUBUPXIQM-VNNZRSTGSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50512105   

TargetSerine protease hepsin(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50512105(CHEMBL4587327)
Affinity DataKi:  0.270nMAssay Description:Inhibition of recombinant human hepsin preincubated for 30 mins followed by Boc-QLR-AMC substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50512105(CHEMBL4587327)
Affinity DataKi:  1.30nMAssay Description:Inhibition of recombinant human matriptase preincubated for 30 mins followed by Boc-QLR-AMC substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50512105(CHEMBL4587327)
Affinity DataKi:  7.20nMAssay Description:Inhibition of recombinant HGFA serine protease domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition by fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50512105(CHEMBL4587327)
Affinity DataKi:  447nMAssay Description:Inhibition of recombinant factor 10a (unknown origin) preincubated for 30 mins followed by chromogenic substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50512105(CHEMBL4587327)
Affinity DataKi:  2.95E+3nMAssay Description:Inhibition of recombinant thrombin (unknown origin) preincubated for 30 mins followed by chromogenic substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed