BDBM50512277 CHEMBL4445615

SMILES OC(=O)C(Cc1c[nH]c2ccccc12)N1C(=S)S\C(=C/c2ccc3cc(OCc4ccc(F)cc4)ccc3c2)C1=O

InChI Key InChIKey=SDBKLCSBUDBMGQ-NUJZUDFISA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50512277   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Yanbian University College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50512277(CHEMBL4445615)
Affinity DataIC50:  450nMAssay Description:Inhibition of human recombinant GST-tagged PTP1B expressed in Escherichia coli BL21 (DE3) using pNPP as substrate measured for 2 mins by colorimetric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Yanbian University College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50512277(CHEMBL4445615)
Affinity DataIC50:  2.85E+4nMAssay Description:Inhibition of human recombinant GST-tagged LAR (catalytic domain 1275 to 1613 residues) expressed in Escherichia coli BL21 (DE3) using pNPP as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Yanbian University College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50512277(CHEMBL4445615)
Affinity DataIC50:  1.52E+3nMAssay Description:Inhibition of human recombinant GST-tagged SHP1 (catalytic domain 244 to 570 residues) expressed in Escherichia coli BL21 (DE3) using pNPP as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Yanbian University College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50512277(CHEMBL4445615)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of human recombinant GST-tagged TCPTP (catalytic domain 41 to 1075 residues) expressed in Escherichia coli BL21 (DE3) using pNPP as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Yanbian University College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50512277(CHEMBL4445615)
Affinity DataIC50:  380nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B expressed in Escherichia coli BL21 (DE3) using pNPP as substrate measured for 2 mins by colorimetri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Yanbian University College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50512277(CHEMBL4445615)
Affinity DataIC50:  4.26E+3nMAssay Description:Inhibition of human recombinant GST-tagged SHP2 (catalytic domain 1116 to 2162 residues) expressed in Escherichia coli BL21 (DE3) using pNPP as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed