BDBM505124 US11066409, Compound I-0059

SMILES CCc1nc(OC)ccc1Nc1nc(=O)cc2CCC(c3cc(F)cc(F)c3)n12

InChI Key InChIKey=ZRJPDULXHKOVFW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 505124   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM505124(US11066409, Compound I-0059)
Affinity DataIC50:  55nMAssay Description:Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM505124(US11066409, Compound I-0059)
Affinity DataIC50:  11nMAssay Description:Evaluation of a human P2X7 receptor inhibitory activity Stably expressing cell line (1321N1 cell transfected with the human P2X7 receptor gene (GenBa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent