BDBM50514065 CHEMBL4570952

SMILES CC(C)NC(=O)c1ccc(c(C)n1)-c1ccc(C[C@H](NC(=O)[C@H]2CC[C@H](CN)CC2)C(=O)Nc2cc(Cl)c3oc(=O)[nH]c3c2)cc1

InChI Key InChIKey=SPPIXACXJIPPBY-PLIGCNLOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514065   

TargetCoagulation factor XI(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50514065(CHEMBL4570952)
Affinity DataIC50:  14nMAssay Description:Inhibition of human factor 11a preincubated for 15 mins followed by Boc-Glu (OBzl) -Ala-Arg-AMC and measured after 30 mins by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50514065(CHEMBL4570952)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by MeOSuc-Ala-Phe-Lys-AMC substrate addition and measured after 30 mins by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed