BDBM50514649 CHEMBL3990456
SMILES Cn1cc(cn1)-c1[nH]c2cc(NC(=O)[C@H](N)C3CCCCC3)cc3c2c1cn[nH]c3=O
InChI Key InChIKey=QTCAZDFUUMEOCL-LJQANCHMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50514649
Affinity DataKd: 2.77E+5nMAssay Description:Binding affinity to BRD9 (unknown origin) assessed as dissociation constant by qPCR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.10E+4nMAssay Description:Binding affinity to BRD7 (unknown origin) assessed as dissociation constant by qPCR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 813nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 105 mins by Rapi...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of recombinant LIMK2 (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 180 mins by Rapi...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of PAK mediated recombinant LIMK2 phosphorylation (347 to 659 residues) (unknown origin) incubated for 45 mins followed by ATP addition me...More data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Inhibition of recombinant LIMK1(unknown origin) expressed in HEK293 cells using NanoGlo substrate incubated for 2 hrs followed by substrate addition ...More data for this Ligand-Target Pair
Affinity DataIC50: 275nMAssay Description:Inhibition of recombinant LIMK2(unknown origin) expressed in HEK293 cells using NanoGlo substrate incubated for 2 hrs followed by substrate addition ...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of LIMK1/LIMK2 in human SH-SY5Y cells assessed as effect on phospho cofilin serine 3 phosphorylation incubated for 2 hr by AlphaLISA SureF...More data for this Ligand-Target Pair
Affinity DataIC50: 174nMAssay Description:Inhibition of PAK mediated recombinant LIMK1 phosphorylation (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition me...More data for this Ligand-Target Pair