BDBM50514776 CHEMBL4465921

SMILES [H][C@@]12CCC[C@]1([H])N([C@@H](C2)c1ncc([nH]1)-c1ccc-2c(c1)-c1ccc(cc-21)-c1cnc([nH]1)[C@@H]1C[C@]2([H])CCC[C@]2([H])N1C(=O)[C@@H](NC(=O)OC)C(C)C)C(=O)[C@@H](NC(=O)OC)C(C)C

InChI Key InChIKey=SPZXVMHBOWLIJQ-AENHMZDESA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50514776   

TargetNonstructural protein 5A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50514776(CHEMBL4465921)
Affinity DataEC50:  0.00300nMAssay Description:Inhibition of NS5A in HCV genotype 1b infected in HuH-Lcu-Neo cells assessed as reduction in viral replication incubated for 48 hrs by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50514776(CHEMBL4465921)
Affinity DataEC50:  0.0100nMAssay Description:Inhibition of NS5A in HCV genotype 1a infected in HuH-Lcu-Neo cells assessed as reduction in viral replication incubated for 48 hrs by luciferase rep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50514776(CHEMBL4465921)
Affinity DataEC50:  4.52nMAssay Description:Inhibition of NS5A in HCV genotype 2a con infected in HuH-Lcu-Neo cells assessed as reduction in viral replication incubated for 48 hrs by luciferase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed