BDBM50517072 CHEMBL4450922
SMILES [O-][N+](=O)CC(c1c([nH]c2ccccc12)-c1ccccc1)c1ccccc1
InChI Key InChIKey=OHZDCJJHWPHZJD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 50517072
Affinity DataKi: 110nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid scintillation spectrometry ana...More data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Displacement of [3H]CP55940 from human CB1R receptor expressed in CHO cell membranes after 60 mins by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Displacement of [3H]SR141716A from human CB1R receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 940nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced beta-arrestin2 recruitment af...More data for this Ligand-Target Pair
Affinity DataEC50: 230nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-stimu...More data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Allosteric agonist activity at N-terminal GFP-tagged rat CB1R expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production a...More data for this Ligand-Target Pair
Affinity DataEC50: 8.10nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskolin-induc...More data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as increase in CP55940-induced beta arrestin2 recruitment af...More data for this Ligand-Target Pair
Affinity DataEC50: 78nMAssay Description:Allosteric agonist activity at human CB1R expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation after 90 mins by hi...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 72nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes assessed as increase in G-protein coupling by measuring [35S]GTPgammaS binding...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Allosteric agonist activity at human CB1R expressed in CHO-K1 cells assessed as increase in beta arrestin2 recruitment after 90 mins by pathhunter be...More data for this Ligand-Target Pair
Affinity DataEC50: 629nMAssay Description:Positive allosteric modulatory activity at human CB1 receptor expressed in CHO-K1 cells assessed as increase in CP55940-induced beta-arrestin recruit...More data for this Ligand-Target Pair
Affinity DataEC50: 303nMAssay Description:Positive allosteric modulatory activity at human CB1 receptor expressed in CHO-K1 cells assessed as increase in CP55940-induced inhibition of forskol...More data for this Ligand-Target Pair
Affinity DataEC50: 260nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP production incubated ...More data for this Ligand-Target Pair
Affinity DataEC50: 650nMAssay Description:Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as beta-arrestin 2 recruitment incubated for 90 mins by PathH...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Positive allosteric modulatory activity at N-terminal GFP-tagged rat CB1R receptor expressed in HEK293 cells assessed as CP55940 EC50 for inhibition ...More data for this Ligand-Target Pair
Affinity DataEC50: 72nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes assessed as increase in [35S]GTPgammaS binding incubated for 30 mins by liquid...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of North Carolina At Greensboro
Curated by ChEMBL
University Of North Carolina At Greensboro
Curated by ChEMBL
Affinity DataEC50: 940nMAssay Description:Positive allosteric modulatory activity at mouse CB1R expressed in CHO-K1 cells assessed as CP55940-induced beta-arrestin2 recruitment by pathhunter ...More data for this Ligand-Target Pair
Affinity DataEC50: 230nMAssay Description:Positive allosteric modulatory activity at human CB1R expressed in CHO-K1 cells assessed as CP55940-induced cAMP level by hit-hunter cAMP assayMore data for this Ligand-Target Pair