BDBM50517431 CHEMBL4471849

SMILES CC(c1cn(C)cn1)n1c(NC2(C)CC2)nc2c(cccc2c1=O)-c1cc2C(=O)N[C@H](C)c2[nH]1

InChI Key InChIKey=KFEFAUXTDOPDKJ-KWCCSABGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50517431   

TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517431(CHEMBL4471849)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of full length recombinant PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50517431(CHEMBL4471849)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of full length recombinant PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed