BDBM50518526 CHEMBL4436695
SMILES COc1ccc(Cn2cc(COc3cc4ncnc(Nc5ccc(F)c(Cl)c5)c4cc3NC(=O)C=C)nn2)cc1
InChI Key InChIKey=IJHIBLXDVDXQDY-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50518526
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Chung-Ang University
Curated by ChEMBL
Chung-Ang University
Curated by ChEMBL
Affinity DataIC50: 212nMAssay Description:Inhibition of human C-terminal His6-tagged ERBB2 (676 to end residues) expressed in baculovirus infected sf21 cells using poly(Glu, Tyr) 4:1 as subst...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human N-terminal GST-tagged EGFR kinase domain (696 to end residues) expressed in baculovirus infected sf21 cells using poly(Glu, Tyr) ...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human N-terminal GST-tagged EGFR T790M/L858R double mutant (696 to end residues) expressed in baculovirus infected sf21 cells using pol...More data for this Ligand-Target Pair