BDBM50518596 CHEMBL4463174
SMILES NC(=O)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1
InChI Key InChIKey=MZLDHCSWGXPGJS-DQEYMECFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50518596
TargetSerine protease hepsin(Homo sapiens (Human))
Washington University School Of Medicine
Curated by ChEMBL
Washington University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged hepsin catalytic domain preincubated for 30 mins followed by Boc-QAR-AMC substrate addition a...More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Washington University School Of Medicine
Curated by ChEMBL
Washington University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 106nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged matriptase catalytic domain expressed in Escherichia coli preincubated for 30 mins followed by...More data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Washington University School Of Medicine
Curated by ChEMBL
Washington University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 4.77E+3nMAssay Description:Inhibition of HGFA catalytic domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition and measured for 1 hr by flu...More data for this Ligand-Target Pair
TargetSerine protease hepsin(Homo sapiens (Human))
Washington University School Of Medicine
Curated by ChEMBL
Washington University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of hepsin (unknown origin) expressed in MCF10A cells preincubated for 30 mins followed by Boc-QAR-AMC substrate addition and measured for ...More data for this Ligand-Target Pair